Preliminary results of treatment of leprosy patients in The Netherlands with daily rifampicin, dapsone and clofazimine.
نویسنده
چکیده
منابع مشابه
Adverse effects from multi-drug therapy in leprosy: a Brazilian study.
INTRODUCTION The WHO MDT for leprosy treatment was officially introduced in Brazil in 1991 and comprises three drugs: dapsone, rifampicin and clofazimine. There are few good studies on the frequency of side-effects attributable to MDT in Brazil. METHODS A retrospective and descriptive study carried out in a LCP in Vitória, State of Espirito Santo, Brazil. A specific and detailed protocol abou...
متن کاملViability and drug sensitivity of M. leprae isolated from long-term WHO/MDT treated multibacillary leprosy patients.
The ALERT Leprosy Control Programme introduced WHOIMDT in Ethiopia in January 1 983 . Paucibacillary patients are treated for 6 months with self-administered daily dapsone and rifampicin once monthly under supervision. Multibacillary patients are treated for a period of at least 2 years or until the skin smears become negative. Treatment consists of self-administered dapsone, clofazimine and ri...
متن کاملHemolytic anemia in patients receiving daily dapsone for the treatment of leprosy.
INTRODUCTION Multidrug therapy for leprosy is currently done with dapsone, clofazimine and rifampicin. Dapsone is known to cause hemolytic anemia (HA) and this adverse event during MDT seems to be more frequent than reported. The aim of this report is to discuss and grade HA due to dapsone during MDT treatment for leprosy. METHODS This is a retrospective study of 194 leprosy patients from a L...
متن کاملAmbulatory treatment of multibacillary leprosy with a regimen of 8 months duration.
An ambulatory treatment regimen for multibacillary leprosy, of 34 weeks duration composed of 8 weeks daily supervised rifampicin, ethionamide (ETH), dapsone (DDS) and clofazimine (CLO) followed by 26 weeks of unsupervised ETH, DDS and CLO, introduced in 1983 has been evaluated; 268 patients were followed for a mean of 4.4 years and a total of 1188 patient years. The relapse rate was 0.33 per 10...
متن کاملEffect of clofazimine and dapsone on rifampicin (Lositril) pharmacokinetics in multibacillary and paucibacillary leprosy cases.
A comparative pharmacokinetic study of Lositril (rifampicin) was carried out in six multibacillary and twelve paucibacillary leprosy cases. The type of leprosy had no significant effect on rifampicin pharmacokinetics. The effect of dapsone and clofazimine when given separately and in combination was studied on rifampicin pharmacokinetics in each group of six patients. Within group comparison re...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Leprosy review
دوره 57 Suppl 3 شماره
صفحات -
تاریخ انتشار 1986